dataverse 10.18130 V3 B35XWX d4d

Datasheet for Dataset - Human Readable Format

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Motivation

Why was the dataset created?

  • Response
    To create AI-ready maps of human cell architecture from disease-relevant cell lines
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Composition

What do the instances represent?

  • Representation
    Cell imaging data
    Instance Type
    Microscopy images
    Data Type
    Immunofluorescence images of protein localization
  • Description
    RO-Crate format using FAIRSCAPE framework
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Collection Process

How was the data acquired?

doi:10.18130/V3/B35XWX
cm4ai-march-2025-release
Cell Maps for Artificial Intelligence - March 2025 Data Release (Beta)
This dataset is the March 2025 Data Release of Cell Maps for Artificial Intelligence (CM4AI; CM4AI.org), the Functional Genomics Grand Challenge in the NIH Bridge2AI program. This Beta release includes perturb-seq data in undifferentiated KOLF2.1J iPSCs; SEC-MS data in undifferentiated KOLF2.1J iPSCs and iPSC-derived NPCs, neurons, and cardiomyocytes; and IF images in MDA-MB-468 breast cancer cells in the presence and absence of chemotherapy (vorinostat and paclitaxel). CM4AI output data are packaged with provenance graphs and rich metadata as AI-ready datasets in RO-Crate format using the FAIRSCAPE framework.
RoleNameORCIDAffiliation
ContributorClark T-University of Virginia
ContributorParker J-University of California, San Diego
ContributorIdeker T-University of California San Diego
  • Description
    Perturb-seq, SEC-MS, and immunofluorescence imaging techniques
  • Description
    Collaboration between UCSD, UCSF, Stanford, UVA, Yale, UA Birmingham, Simon Fraser University, and the Hastings Center
Description
March 2025 Data Release (Beta)
Description
Data packaged with provenance graphs and rich metadata as AI-ready datasets
  • AI
  • artificial intelligence
  • breast cancer
  • Bridge2AI
  • cardiomyocyte
  • CM4AI
  • CRISPR/Cas9
  • induced pluripotent stem cell
  • machine learning
  • mass spectroscopy
  • protein localization
  • single-cell RNA sequencing
University of Virginia Dataverse
2025-03-20
beta
NIH Bridge2AI program
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Uses

What (other) tasks could the dataset be used for?

  • Response
    Functional genomics and cellular mapping for artificial intelligence applications
Description
Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International license (CC BY-NC-SA 4.0)
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Maintenance

How will the dataset be maintained?

Beta
Generated on 2025-11-09 10:17:35 using Bridge2AI Data Sheets Schema