# dataverse 10.18130 V3 B35XWX d4d

Datasheet for Dataset - Human Readable Format

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## Motivation

Why was the dataset created?

Purposes

- Response
    To create AI-ready maps of human cell architecture from disease-relevant cell lines

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## Composition

What do the instances represent?

Instances

- Representation
    Cell imaging data
  Instance Type
    Microscopy images
  Data Type
    Immunofluorescence images of protein localization

Distribution Formats

- Description
    RO-Crate format using FAIRSCAPE framework

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## Collection Process

How was the data acquired?

ID *
doi:10.18130/V3/B35XWX
Name
cm4ai-march-2025-release
Title
Cell Maps for Artificial Intelligence - March 2025 Data Release (Beta)
Description
This dataset is the March 2025 Data Release of Cell Maps for Artificial Intelligence (CM4AI; CM4AI.org), the Functional Genomics Grand Challenge in the NIH Bridge2AI program. This Beta release includes perturb-seq data in undifferentiated KOLF2.1J iPSCs; SEC-MS data in undifferentiated KOLF2.1J iPSCs and iPSC-derived NPCs, neurons, and cardiomyocytes; and IF images in MDA-MB-468 breast cancer cells in the presence and absence of chemotherapy (vorinostat and paclitaxel). CM4AI output data are packaged with provenance graphs and rich metadata as AI-ready datasets in RO-Crate format using the FAIRSCAPE framework.
Creators

Role | Name | ORCID | Affiliation
--- | --- | --- | ---
Contributor | Clark T | - | University of Virginia
Contributor | Parker J | - | University of California, San Diego
Contributor | Ideker T | - | University of California San Diego

Collection Mechanisms

- Description
    Perturb-seq, SEC-MS, and immunofluorescence imaging techniques

Maintainers

- Description
    Collaboration between UCSD, UCSF, Stanford, UVA, Yale, UA Birmingham, Simon Fraser University, and the Hastings Center

Collection Timeframe

Description
  March 2025 Data Release (Beta)

Preprocessing Strategies

Description
  Data packaged with provenance graphs and rich metadata as AI-ready datasets

Keywords

- AI
- artificial intelligence
- breast cancer
- Bridge2AI
- cardiomyocyte
- CM4AI
- CRISPR/Cas9
- induced pluripotent stem cell
- machine learning
- mass spectroscopy
- protein localization
- single-cell RNA sequencing

Publisher
University of Virginia Dataverse
Issued
2025-03-20
Status
beta
Was Derived From
NIH Bridge2AI program
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## Uses

What (other) tasks could the dataset be used for?

Tasks

- Response
    Functional genomics and cellular mapping for artificial intelligence applications

License And Use Terms

Description
  Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International license (CC BY-NC-SA 4.0)

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## Maintenance

How will the dataset be maintained?

Version
Beta
Generated on 2025-11-09 10:17:35 using Bridge2AI Data Sheets Schema