Type: Package
Package: Pmetrics
Title: Pmetrics for Population Modeling and Simulation
Version: 3.2.2
Authors@R: c(
    person("Michael", "Neely", , "mneely@usc.edu", role = c("aut", "cre")),
    person("Julián", "Otálvaro", , "juliandavid347@gmail.com", role = "aut"),
    person("Markus", "Hovd", role = "aut"),
    person("Walter", "Yamada", role = "ctb"),
    person("Alan", "Schumitzky", role = "ctb"),
    person("Rong", "Chen", role = "ctb"),
    person("Michael", "van Guilder", role = "ctb"),
    person("David", "Bayard", role = "ctb"),
    person("Robert", "Leary", role = "ctb")
  )
Description: Pmetrics is short for pharmacometrics, the discipline of
    modeling drug kinetics and effects on biologic systems, including
    disease progression. Models can be used to simulate novel therapeutic
    dosing regimens and/or populations, informing trial design and dosing
    strategies. The package supports primarily non-parametric but aims to support
    parametric pharmacometric modeling and simulation with functions to
    run and analyze the output from all three components of the Pmetrics
    software suite for population pharmacometric data analysis.
License: GPL (>= 3)
URL: https://lapkb.github.io/Pmetrics/
BugReports: https://github.com/LAPKB/Pmetrics/issues
Depends: 
    R (>= 4.2)
Imports:
    bslib,
    cli,
    clipr,
    crayon,
    dplyr,
    DT,
    flextable,
    ggplot2,
    glue,
    graphics,
    grDevices,
    grid,
    htmltools,
    htmlwidgets,
    jsonlite,
    knitr,
    lifecycle,
    lubridate,
    magrittr,
    MASS,
    openxlsx,
    parallel,
    plotly,
    progress,
    purrr,
    R6,
    RColorBrewer,
    readr,
    reticulate,
    rlang,
    rmarkdown,
    shiny,
    stats,
    stringr,
    tibble,
    tidyr,
    tools,
    trelliscopejs,
    utils,
    withr
Additional_repositories: https://lapkb.r-universe.dev
Suggests:
    covr,
    devtools,
    mclust,
    PmetricsReports,
    PmetricsLitSim,
    PmetricsPlot,
    PmetricsModelLib,
    npde,
    testthat
VignetteBuilder: 
    knitr
Config/Needs/website: r-lib/pkgdown, quarto
Config/rextendr/version: 0.5.0
Config/roxygen2/version: 8.0.0
Config/testthat/edition: 3
Encoding: UTF-8
LazyData: true
LazyDataCompression: xz
Roxygen: list(markdown = TRUE)
SystemRequirements: Cargo (>= 1.82) (Rust's package manager), rustc
