LOCUS       NC_004297_REF               7279 bp ss-RNA     linear   VRL 13-AUG-2018
DEFINITION  Lassa virus segment L, complete sequence.
ACCESSION   NC_004297_REF
VERSION     NC_004297_REF.1
DBLINK      BioProject: PRJNA485481
KEYWORDS    RefSeq.
SOURCE      Mammarenavirus lassaense
  ORGANISM  Mammarenavirus lassaense
            Viruses; Riboviria; Orthornavirae; Negarnaviricota;
            Polyploviricotina; Ellioviricetes; Bunyavirales; Arenaviridae;
            Mammarenavirus.
REFERENCE   1  (bases 1 to 7279)
  AUTHORS   Djavani,M., Lukashevich,I.S., Sanchez,A., Nichol,S.T. and
            Salvato,M.S.
  TITLE     Completion of the Lassa fever virus sequence and identification of
            a RING finger open reading frame at the L RNA 5' End
  JOURNAL   Virology 235 (2), 414-418 (1997)
   PUBMED   9281522
REFERENCE   2  (bases 1 to 7279)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-APR-2007) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   3  (bases 1 to 7279)
  AUTHORS   Djavani,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-1999) Pathology, University of Wisconsin, 1300
            University Ave., SMI, Rm.#512, Madison, WI 53706, USA
  REMARK    Sequence update by submitter
REFERENCE   4  (bases 1 to 7279)
  AUTHORS   Djavani,M., Lukashevich,I., Sanchez,A., Nichol,S.T. and
            Salvato,M.S.
  TITLE     Direct Submission
  JOURNAL   Submitted (01-OCT-1996) Pathology and Laboratory Medicine,
            University of Wisconsin-Madison, 1300 University Ave, 512 SMI,
            Madison, WI 53706, USA
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from U73034.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..7279
                     /organism="Mammarenavirus lassaense"
                     /mol_type="genomic RNA"
                     /strain="Josiah"
                     /db_xref="taxon:3052310"
                     /segment="L"
     gene            66..365
                     /gene="Z"
                     /locus_tag="Z"
                     /db_xref="GeneID:956586"
     CDS             66..365
                     /gene="Z"
                     /locus_tag="Z"
                     /note="ring finger protein"
                     /codon_start=1
                     /product="Z protein"
                     /protein_id="NP_694871.1"
                     /db_xref="GeneID:956586"
                     /translation="MGNKQAKAPESKDSPRASLIPDATHLGPQFCKSCWFENKGLVEC
                     NNHYLCLNCLTLLLSVSNRCPICKMPLPTKLRPSAAPTAPPTGAADSIRPPPYSP"
     gene            complement(466..7122)
                     /gene="L"
                     /locus_tag="L"
                     /db_xref="GeneID:956587"
     CDS             complement(466..7122)
                     /gene="L"
                     /locus_tag="L"
                     /note="L polymerase"
                     /codon_start=1
                     /product="L protein"
                     /protein_id="NP_694872.1"
                     /db_xref="GeneID:956587"
                     /translation="MEEDIACVKDLVSKYLVDNERLSRQKLAFLVQTEPRMLLMEGLK
                     LLSLCIEVDSCNANGCEHNSEDKSVERILHDHGILTPSLCLWYPDGYKLTGNVLILLE
                     CFVRSSPANFEQKYIEDFKKLEQLKEDLKSVDINLIPLIDGRTSFYNEQIPDWVNDKL
                     RDTLFSLLKYAQESNSLFEESEYSRLCESLFMTSGRLSGVESLNVLMDNRSNHYEEVI
                     ASCHQGINNKLTAHEVKLQIEEEYQVFRNRLRKGEIEGQFLKVDKSQLLNELNNLYAD
                     KVVAEDNIEHLIYQFKRASPILRFLYANVDEGNEKRGNQTIGECQVQCWRSFLNKVKS
                     LRILNTRRKLLLIFDALILLASKHDLMKQKCLKGWLGSCFLRVKDRLVSLEATKRDLE
                     KWGERGNRLRSRITQSSQCLSKNQILNSIFQKTILKATTALKDVGISVDHYKIDMEVI
                     CLNSYDLIMDFDVSGVVPTISYQRTEEETFPYVMGDVELLGTTDLERLSSLSLALVNS
                     MKTSSTVKLRQNEFGPARYQVVRCKEAYCQEFSLGNTELQLIYQKTGECSKCYAINDN
                     KVGEVCSFYADPKRYFPAIFSAEVLQTTISTMISWIEDCNELEGQLNNIRSLTKMILV
                     LILAHPSKRSQKLLQNLRYFVMAYLSDYHHKDLIDKIREELITDVEFLLYRLIRTLMN
                     LVLSEDVKSMMTNRFKFILNVSYMCHFITKETPDRLTDQIKCFEKFLEPKVRFGHVST
                     NPADTATEEELDDMVYNAKKFLSKDGCTTIEGPDYKRPGVSKKYLSLLTSSFNNGSLF
                     KEREVKREIKDPLITSGSAALDLASKKSVVVNKYTDGSRILNYDFNKLTALAVSQLTE
                     VFSRKGKYLLNKQDYEYKVQQAMSNLVLGSGQLKSDADGADLDEILLDGGASDYFDQL
                     KETVEKIVDQYREPVKLGSGPNGDGQPSINDLDEIVSNKFYIRLIKGELSNHMVEEFD
                     HDILPGKFYEEFCNAVYENSRLKQKYFYCGHMSQCPIGELTKAVSTRTYFNHEYFQCF
                     KSILLIMNANTLMGRYTHYKSRNLNFKFDMGKLSDDVRISERESNSEALSKALSLTNC
                     TTAMLKNLCFYSQESPQSYDSVGPDTGRLKFSLSYKEQVGGNRELYIGDLRTKMFTRL
                     IEDYFEAISLQLSGSCLNNEKEFENAILSMKLNVSLAHVSYSMDHSKWGPMMCPFLFL
                     TVLQNLIFLSKDLQADIKGRDYLSTLLMWHMHKMVEIPFNVVTAMMKSFIKAQLGLRK
                     KTKQSITEDFFYSNFQAGVVPSHISSILDMGQGILHNTSDFYALISERFINYAISCIC
                     GGTIDAYTSSDDQISLFDQSLTELLQRDPEEFRTLIEFHYYMSDQLNKFVSPKSVIGR
                     FVAEFKSRFFVWGDEVPLLTKFVAAALHNIKCKEPHQLAETIDTIIDQSVANGVPVHL
                     CNLIQKRTLNPLQYARYPIDPFLLNCETDVRDWVDGNRSYRIMRQIEGLIPNACSKIR
                     SMLRKLYNRLKTGQLHEEFTTNYLSSEHLSSLRNLCELLDVEPPSESDLEYSWLNLAA
                     HHPLRMVLRQKIIYSGAVNLDDEKIPTIVKTIQNKLSSTFTRGAQKLLSEAINKSAFQ
                     SSIASGFVGLCRTLGSKCVRGPNKENLYIKSIQSLISDVKGIKLLTNSNGIQYWQVPL
                     ELRNGSGGESVVSYFRPLLWDYMCISLSTAIELGAWVLGEPKTVKVFDFFKHNPCDYF
                     PLKPTASKLLEDRVGLNHIIHSLRRLYPSVFEKHILPFMSDLASTKMKWSPRIKFLDL
                     CVALDVNCEALSLVSHIVKWKREEHYIVLSSELRLSHSRTHEPMVEERVVSTSDAVDN
                     FMRQIYFESYVRPFVATTRTLGSFTWFPHKTSVPEGEGLHRMGPFSSFVEKVIHKGVE
                     RPMFKHDLMMGYAWIDFDIEPARFNQNQLIASGLVDPKFDSLEDFFDAVASLPPGSAK
                     LSQTVRFRVKSQDASFKESFAIHLEYTGSMNQQAKYLVHDVTVMYSGAVSPCVLSDCW
                     RLVLSGPTFKGKSAWYVDTEIINEFLIDTNQLGHVTPVEIVVDMERLQFTEYDFVLVG
                     PCTEPTPLVVHRGGLWECGKKLASFTPVIQDQDLEIFVREVGDTSSDLLIGALSDMMI
                     DRLGLRMQWSGVDIVSTLRAAAPSCEGILSAVLEAVDNWVEFKGYALCYSKSRGKVMV
                     QSSGGKLRLKGRTCEELTRKDECIEDIE"
ORIGIN
        1 cgcaccgggg atcctaggca atttggttgt ctttttttga ggccttgtgc gctgtacttc
       61 tccaaatggg aaacaagcaa gccaaagccc cagaatcaaa agacagtccg agagccagcc
      121 tgatcccaga tgccacacat ctagggccac agttctgtaa gagctgctgg ttcgaaaaca
      181 agggcctggt tgagtgcaac aaccactatc tgtgtctcaa ctgcctcacc ttacttctaa
      241 gtgtcagcaa caggtgtccc atttgcaaga tgcctctccc cacaaaactg agaccatcag
      301 ccgctccaac agcacctcca accggagcag cggacagcat cagaccccca ccctacagtc
      361 cctgaatctc ccaccgaccc ccaccactcc catcctcccc ccgacacccc ccggggggac
      421 cccccgccgg gggccccccc gggggagcca accatcacca aaaaactact caatgtcttc
      481 gatgcattca tccttcctag tcagctcctc acatgttctg cccttcaatc tcaatttacc
      541 accacttgat tgtaccatca cctttcccct tgacttacta taacagagag cataaccctt
      601 gaactccacc cagttgtcca ctgcctcaag aaccgcactc aagatcccct cacaactcgg
      661 cgctgcagcc ctaagtgtgg agacaatgtc cacccctgac cactgcatcc ttaaccccag
      721 cctgtctatc atcatatcac tcaatgcccc aatcagcagg tcagacgaag tgtccccaac
      781 ctctctcaca aatatctcaa gatcctggtc ttgtataaca ggtgtaaagg atgccaattt
      841 ctttccacat tcccacaagc ctcccctatg cacaaccagg ggggttggtt cagtgcaagg
      901 acccaccaat acaaagtcat actccgtaaa ctgcaacctt tccatatcaa caacaatctc
      961 aacaggggtc acatgcccta gttgatttgt gtcaattaaa aactcattaa tgatctcggt
     1021 gtcaacatac catgctgatt tgcccttgaa agtaggtcct gacaaaacca gtctccaaca
     1081 gtctgacaag acacacggac tcactgcacc tgagtacata acggttacat catgtactag
     1141 atacttggcc tgttgattca ttgagccagt atactcaagg tggatggcaa agctttcctt
     1201 aaaactagca tcttgacttt taacacggaa cctcactgtc tgactcagtt ttgcagaccc
     1261 tggaggtagt gaagctacgg catcaaagaa atcctccaat gagtcaaact taggatcaac
     1321 taaacctgat gcgatcaatt gattttgatt gaatctagct ggctcaatat caaagtctat
     1381 ccaagcataa cccatcatca gatcatgctt aaacattggc ctttcaacac ctttgtgaat
     1441 aactttctct acaaatgaag aaaatggacc cattctatgc aacccttcac cctctggaac
     1501 tgatgtcttg tgtggaaacc acgtgaagga ccccaatgtt cttgtagtcg caacaaatgg
     1561 tctcacgtaa gactcaaaat aaatttgcct catgaaattg tcaacagcat cactagtgct
     1621 cactactctt tcttccacca tgggttcatg tgtcctactg tgagacaacc tcaattcaga
     1681 tgataacaca atgtaatgtt cctctctttt ccattttact atgtgtgaga caagagacaa
     1741 ggcttcacag ttaacatcca acgctacaca gagatctaga aattttattc tgggtgacca
     1801 cttcattttg gttgacgcta gatcgctcat gaatggtaat atgtgtttct caaacactga
     1861 tgggtacagc cttcttaaag aatgaatgat gtgattcaaa ccaaccctat cctccaatag
     1921 ttttgatgca gttggcttta agggaaaata gtcacaaggg ttatgtttga aaaaatcaaa
     1981 caccttaact gtcttaggtt cccctaagac ccatgcaccc agttctattg cagttgataa
     2041 ggagatgcac atataatccc ataacaaggg tctgaaataa ctgaccacac tttcacctcc
     2101 acttccattt ctaagttcta gcggaacttg ccaatattga atgccattag aatttgtcaa
     2161 caatttgatt cccttgacat cagaaatcag agactgaatg gacttaatat acagattctc
     2221 tttatttggt ccccgaacac atttgctacc caatgttctg cacaatccta caaagccaga
     2281 tgcaatggaa ctttggaatg cagatttgtt gatagcttca gacagcaatt tttgcgcacc
     2341 tcgagtgaaa gtggaagaca acttattttg gattgttttg acaatggtag gaatcttctc
     2401 atcatctagg ttcacagcac ctgaatatat tatcttttgt ctcaacacca ttcttaaagg
     2461 atgatgcgca gccaagttta gccaagaata ctcaaggtca gactcagatg ggggctcaac
     2521 atccaacagc tcacaaagat ttcttagtga tgagaggtgc tcactagaca aatagtttgt
     2581 tgtgaactct tcatggagtt gcccagtctt caacctattg tacagttttc ttaacataga
     2641 tctaatcttg ctgcaagcat taggaatcaa tccctctatt tgcctcataa tcctataact
     2701 acggttgcca tctacccagt ctctaacatc tgtctcgcaa ttcaataaga atgggtcaat
     2761 agggtatctt gcatattgca aaggatttaa ggttcttttc tgtattagat tacataagtg
     2821 aacagggaca ccattcgcaa ccgactgatc aatgattgtg tcaattgttt ctgccagttg
     2881 gtgtggctct ttacacttta tattgtgaag agctgctgca acgaactttg tcaataatgg
     2941 cacttcatct ccccaaacaa aaaatctaga tttaaactct gcaacaaacc tgccaatgac
     3001 acttttaggg ctcacaaact tattgagttg atcactcata taatagtgga actctattag
     3061 agtcctaaat tcttctgggt ctctttgcaa aagctctgtg agagattgat caaagagaga
     3121 aatctgatca tcactagagg tataagcatc tatcgtacca ccgcatatac aactgatagc
     3181 ataattaatg aacctctctg aaatgagggc ataaaaatct gatgtgttgt gtaatattcc
     3241 ttgacccatg tcaagtattg aactgatgtg agaaggcact acaccagctt ggaaattaga
     3301 gtaaaagaaa tcttctgtta ttgactgttt agttttcttc cttaacccta gttgggcttt
     3361 aatgaaagac ttcatcatgg ctgtcaccac attaaaaggt atttccacca ttttgtgcat
     3421 atgccacata agtagggttg agagatagtc cctccctttt atgtcagctt gcaagtcctt
     3481 tgagaggaaa attaaattct gtaagacagt caagaacaaa aatggacaca tcattgggcc
     3541 ccacttacta tgatccatgc tataagacac atgtgccaat gaaacattca atttcatgga
     3601 aaggatagca ttttcaaatt ccttctcgtt gttcaggcaa ctccctgata actgtaggct
     3661 tatagcttca aagtaatctt ctataagtct agtaaacatc tttgttctaa gatcaccaat
     3721 atataattct ctgttaccac ccacttgttc tttatatgac aaagaaaact taagccttcc
     3781 tgtatcaggt cccactgagt cataagattg tggcgactct tggctataaa aacacaaatt
     3841 ctttaacatt gctgtggtac agtttgtcag tgacagagcc ttactaagtg cctctgaatt
     3901 gctctccctt tcactaattc ttacatcatc agagagttta cccatatcaa acttgaaatt
     3961 aaggttcctt gacttataat gagtgtacct ccccataagt gtattcgcat tcatgatcaa
     4021 gagtatggac ttaaaacact gaaagtattc atggttaaag tatgtccttg ttgacactgc
     4081 ctttgtcaac tctccaatag gacactgtga catatgtcca cagtaaaaat acttctgctt
     4141 caatctacta ttctcataga cagcattaca gaattcttca taaaatttac ctggtaagat
     4201 atcatgatca aactcctcaa ccatgtgatt ggataattca cccttgatca acctaatgta
     4261 aaacttattt gagacaatct catctagatc atttattgat ggttggccat caccattagg
     4321 gcctgagcct agcttgacag gttccctata ctgatcaaca attttttcaa cagtctcctt
     4381 tagctgatca aaataatcgc ttgcacctcc atcgagcaaa atttcgtcta ggtcagcccc
     4441 atcagcatca cttttgagct gcccagatcc tagaaccaaa ttgctcattg cctgctgaac
     4501 tttgtactca tagtcctgct tgttgagaag gtactttcct ttccttgaga agacttcagt
     4561 gagctgcgac acggccagtg ctgtgagctt attgaagtca tagtttaata ttctagaacc
     4621 atctgtgtat ttattaacaa caacactttt cttgctggct aaatccaagg ctgcactgcc
     4681 actggtgatg agaggatctt tgatttccct ttttacttcc ctctccttaa atagtgaacc
     4741 attgttaaaa gaggatgtaa gaagagataa atacttcttt gaaacaccag gccttttata
     4801 atctggtccc tcgatagttg tgcatccatc tttacttaaa aacttttttg cattgtagac
     4861 catgtcatcc aattcttcct cagtggctgt gtctgcagga ttagtgctca catgaccaaa
     4921 tctcaccttt ggttccagaa acttctcaaa acattttatc tgatctgtca atctatctgg
     4981 tgtttctttc gtaatgaagt ggcacatgta ggaaacattc aaaatgaact tgaacctatt
     5041 agtcatcatg ctcttcacat cctcagataa aaccagattc attaatgtcc ttattaacct
     5101 atagagcagg aactcaacat cagtgattaa ttcttccctt attttgtcaa tgaggtcctt
     5161 atgatgataa tctgatagat aagccattac aaagtaccta agattttgga ggagcttttg
     5221 agaacgttta ctggggtgag ctaaaattaa aaccaggatc atctttgtca gagacctgat
     5281 attgttcaac tgcccttcca gctcattgca atcttctatc caagaaatca tagtgcttat
     5341 tgttgtttgt aaaacctcag ctgaaaatat tgctggaaaa tatcttttag gatcagcata
     5401 aaatgagcac acctcaccaa ctttgttatc attaatagca tagcacttcg agcactcccc
     5461 tgtcttttga taaatcagtt gtaattcagt gttacccaat gaaaactctt gacaatatgc
     5521 ttctttgcat ctgaccactt gataccttgc gggtccaaat tcattctgtc tcagctttac
     5581 ggtagaagaa gttttcatag agttcaccaa agcgaggctc aatgaggaaa gtctctctaa
     5641 gtcagtggtt cccagtagtt ccacatcccc catcacataa gggaatgttt cttcctctgt
     5701 tctctgataa ctgattgttg ggacaactcc ggagacatca aagtccataa tcaaatcata
     5761 gctgttaagg cagatcacct ccatatcaat tttatagtgg tccacactga tcccaacatc
     5821 ctttaaagca gtggtggcct tcaaaatggt tttctggaat attgaattga ggatttgatt
     5881 cttactcaaa cactgggagg actgtgtgat tctagatctt agcctgttgc ctcgctctcc
     5941 ccatttctcg agatccctct ttgttgcctc caaagaaact agtctatctt taactcttaa
     6001 gaagcaagac cccaaccacc cttttaaaca cttttgtttc atcaggtcat gcttacttgc
     6061 aaggagaatt agtgcatcaa aaattaatag aagtttcctc cttgtgttca atatcctcaa
     6121 agattttact ttatttagga atgatctcca gcattgaacc tgacattctc caatagtttg
     6181 gtttcccctt ttttcattcc cctcatcaac atttgcatac aaaaatctca atattggtga
     6241 tgctctcttg aactggtaaa ttaagtgttc gatattgtct tctgcaacta ccttatcagc
     6301 gtacaaattg ttaagctcat taagtaactg gctcttatca acctttaaaa actgaccttc
     6361 tatctctcct ttcctcaatc tgttcctaaa cacttgatac tcctcttcga tctgcagctt
     6421 tacctcatga gctgttaatt tattattgat gccctggtgg catgaggcaa tcacttcctc
     6481 ataatgatta gagcgattgt ccatcagaac atttaaactc tccacccctg ataatctacc
     6541 cgaagtcatg aataaagatt cacagagtct gctatactct gactcttcaa aaagtgaatt
     6601 actctcctgt gcatacttta aaagtgagaa gagcgtatcc ctcaacttat cattgaccca
     6661 gtcaggtatt tgttcattgt agaatgatgt tctcccgtct ataagtggta ttaaattgat
     6721 gtcgacactc ttcaggtctt ctttcagctg ctctaatttt ttgaagtcct caatgtactt
     6781 ctgctcaaag ttagcaggag atgatctaac aaaacactcc agcagtatta gaacattgcc
     6841 cgtcagtttg taaccgtccg ggtaccacaa acatagtgaa ggtgtcaaga ttccatggtc
     6901 atggagaatt ctttccacag atttgtcctc actgttatgc tcgcaaccat ttgcgttgca
     6961 agaatcaacc tcaatacaga gggacaagag tttcaaccct tccattaata gcatcctagg
     7021 ctctgtctgc acaagaaatg ctaacttctg tcttgacaat ctctcgttgt ccactaggta
     7081 ttttgatact aagtctttga cacaggctat gtcttcctcc atgtttagct gcaggtatga
     7141 tgttcagaac cctcagaaca tgtggtctgc tagagcaaca gttcgctatg ggatagggtc
     7201 ccgtaggggc acagaagaca caagaggcaa ttaaagacaa ttaaataaga tagccttaat
     7261 gcctaggatc ctcggtgcg
//
