Test

## [1] "SafetyWindowSize"

To protect the welfare of individual participants, the rate of enrolment within each cohort will be restricted.

For cohort sizes of less than 4

• The gap between the enrolment of the first and the second participants in the cohort should be at least 7 days
• The gap between all subsequent participants should be at least 3 days

For cohort sizes of 4 or more

• The gap between the enrolment of the first and the second participants in the cohort should be at least 9 days
• The gap between all subsequent participants should be at least 5 days

For all cohorts, before the next cohort can open, all participants in the current cohort must have been followed up for at least 7 days and at least one participant must have been followed up for at least 14 days.