## [1] "NextBestNCRM"

The dose recommended for the next cohort will be chosen in the following way. First, doses that are ineligible according to the increments rule will be discarded. Next, any dose for which the mean posterior probability of toxicity being in the overdose range - (0.35, 1] - is 0.25 or more will also be discarded. Finally, the dose amongst those remaining which has the highest chance that the mean posterior probability of toxicity is in the target toxicity range of 0.2 to 0.35 (inclusive) will be selected.